Description

L-Norvaline, 5-Hydroxy-2-Methyl- (9Ci) is a non-proteinogenic amino acid derivative with a unique hydroxylated side chain. This compound is valued as a specialized chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and chemical manufacturers in the life sciences sector for developing novel compounds, including potential active pharmaceutical ingredients (APIs) and biochemical probes. Its specific stereochemistry and functional groups make it a critical component for asymmetric synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor analog in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships (SAR) and modify peptide properties.
• Asymmetric Synthesis: Acts as a chiral auxiliary or building block for the construction of complex molecules with defined stereochemistry.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Chemical Biology: Utilized in the design and synthesis of molecular probes for studying biological processes.

Basic Information

Product Name	L-Norvaline, 5-Hydroxy-2-Methyl- (9Ci)
CAS No.	160187-05-3
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	5-Hydroxy-2-methyl-L-norvaline; (2S)-2-Amino-5-hydroxy-2-methylpentanoic acid; L-2-Amino-5-hydroxy-2-methylvaleric acid; 2-Methyl-5-hydroxynorvaline; (S)-2-Amino-5-hydroxy-2-methylpentanoic acid; 5-Hydroxy-2-methylnorvaline; L-5-Hydroxy-2-methylnorvaline
EINECS	Contact for details

Quality Control

Our L-Norvaline, 5-Hydroxy-2-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.