Description

Benzaldehyde, 4-(Difluoromethoxy)-3-(1-Methylethoxy)- is a specialized aromatic aldehyde derivative, distinguished by its difluoromethoxy and isopropoxy substituents. This compound serves as a high-value chemical intermediate for synthesizing advanced molecules in pharmaceutical and agrochemical research. It is primarily required by R&D chemists and process development scientists working on novel active ingredients, where its unique substitution pattern enables the introduction of specific functionalities. The product is supplied with a CAS Number of 159783-82-1, ensuring precise identification and traceability.

Application

This substituted benzaldehyde is a versatile building block designed for advanced synthetic chemistry. Its primary applications include:

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can improve pesticidal activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a starting material for creating advanced organic electronic materials, where its aromatic core and ether linkages contribute to desired electronic and structural properties.
• Fine Chemical & Flavor/Fragrance Research: Employed in the exploration of new aromatic compounds for specialty chemicals and high-value organoleptic applications.
• Cross-Coupling Reactions: The aldehyde functionality makes it a suitable substrate for various palladium-catalyzed and other metal-mediated coupling reactions to construct complex molecular architectures.

Basic Information

Product Name	Benzaldehyde, 4-(Difluoromethoxy)-3-(1-Methylethoxy)-
CAS No.	159783-82-1
Molecular Formula	C11H12F2O3
Molecular Weight	230.21 g/mol
Synonyms	4-(Difluoromethoxy)-3-isopropoxybenzaldehyde; 3-Isopropoxy-4-(difluoromethoxy)benzaldehyde; Benzaldehyde, 3-(1-methylethoxy)-4-(difluoromethoxy)-; 4-(Difluoromethoxy)-3-(1-methylethoxy)benzaldehyde; 3-(Isopropoxy)-4-(difluoromethoxy)benzaldehyde; 159783-82-1; 4-Difluoromethoxy-3-isopropoxy-benzaldehyde
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 4-(Difluoromethoxy)-3-(1-Methylethoxy)- is produced and handled under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by HPLC), identity confirmation (by IR and/or NMR), and impurity profiles. Our quality commitment ensures the material meets the exacting standards required for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.