Description

2-Bromo-4-(Pentafluorothio)Aniline, 97% is a high-purity organofluorine building block characterized by its unique combination of bromine and pentafluorothio substituents on an aniline core. This compound matters as a versatile and critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), where its specific functional groups enable precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting sulfur- and fluorine-containing bioactive molecules.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging the biological activity imparted by the pentafluorothio group.
• Material Science: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics and potential for cross-coupling reactions.
• Chemical Synthesis: Acts as a versatile reagent in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki reactions) where the bromine serves as a handle for further functionalization.
• Fluorinated Compound Library Synthesis: Essential for creating diverse libraries of fluorinated compounds for high-throughput screening in drug discovery and material science.

Basic Information

Product Name	2-Bromo-4-(Pentafluorothio)Aniline, 97%
CAS No.	159727-25-0
Molecular Formula	C6H3BrF5NS
Molecular Weight	296.06 g/mol
Synonyms	2-Bromo-4-(pentafluorosulfanyl)aniline; 4-Amino-3-bromopentafluorothiobenzene; Benzenamine, 2-bromo-4-(pentafluorothio)-; 2-Bromo-4-pentafluorosulfanylaniline; 2-Br-4-SF5-Aniline; 2-Bromo-4-SF5-aniline; 2-Bromo-4-(SF5)aniline; CAS 159727-25-0
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Pentafluorothio)Aniline, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.