Description

Fmoc-L-2-Furylalanine CAS NO 159611-02-6 is a protected, non-proteinogenic amino acid derivative featuring a furan side chain, essential for advanced peptide synthesis. This specialized building block is critical for introducing unique structural motifs and enhancing the biophysical properties of synthetic peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid for the automated synthesis of complex peptides.
• Medicinal Chemistry & Drug Discovery: For incorporating the furylalanine moiety into lead compounds to modulate activity, solubility, or metabolic stability.
• Peptidomimetic Design: Serves as a key scaffold for creating non-natural peptide analogs with enhanced pharmacological profiles.
• Bioconjugation & Probe Development: Used in the synthesis of labeled peptides for biochemical assays and diagnostic applications.
• Academic & Industrial Research: A valuable reagent for studying protein-protein interactions and structure-activity relationships (SAR).
• Combinatorial Chemistry Libraries: For generating diverse compound libraries to screen for new biological activities.

Basic Information

Item	Details
Product Name	Fmoc-L-2-Furylalanine
CAS No.	159611-02-6
Molecular Formula	C22H19NO5
Molecular Weight	377.39 g/mol
Synonyms	Fmoc-2-Furylalanine; Fmoc-L-β-(2-Furyl)-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-furyl)-L-alanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-(furan-2-yl)propanoic acid; Fmoc-Fur(2)-OH; Fmoc-2-Fua-OH; Nα-Fmoc-L-2-furylalanine; L-2-Furylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our Fmoc-L-2-Furylalanine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is light-sensitive (store away from light). For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.