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Drosomycin CAS NO 159522-55-1


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CAS No.:159522-55-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Drosomycin is a potent antifungal peptide originally isolated from *Drosophila melanogaster*, representing a key component of the innate immune response in insects. This compound is of significant interest for its role as a model defensin in immunological research and for its potential in developing novel antimicrobial agents. It is primarily utilized by researchers in the fields of biochemistry, molecular biology, and pharmaceutical development to study host-pathogen interactions and innate immunity mechanisms.

Application

  • Biomedical Research: Used as a reference standard and active agent in studies of innate immunity, antifungal defense mechanisms, and peptide structure-activity relationships.
  • Antimicrobial Development: Serves as a lead compound or template for the design and synthesis of novel antifungal peptides and therapeutics.
  • Biochemical Assays: Employed in in vitro assays to evaluate antifungal activity against various pathogenic fungi, including Candida and Aspergillus species.
  • Cell Biology Studies: Applied in research to understand signal transduction pathways and cellular responses triggered by antimicrobial peptides.
  • Comparative Immunology: Facilitates comparative studies between insect and mammalian immune systems.
  • Pharmaceutical R&D: Investigated for potential applications in topical antifungal formulations or as a coating for medical devices.

Basic Information

Product Name Drosomycin
CAS No. 159522-55-1
Molecular Formula C202H310N56O57S8
Molecular Weight ~4635.6 g/mol
Synonyms Drosomycin; Drosophila Antifungal Peptide; Insect Defensin Drosomycin; DRS; CG10816-PA; Fly Antifungal Peptide
EINECS Contact for details

Quality Control

Our Drosomycin is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and high biological activity. Each lot is characterized using advanced analytical techniques, including HPLC for purity assessment and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, potency, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white lyophilized powder
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95%
Peptide Content ≥ 80% (by weight)
Water Content (KF) ≤ 5.0%
Biological Activity Assayed by antifungal activity
Endotoxin Level < 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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