Description

2-(Benzyloxy)-4-Fluoroaniline is a versatile aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a protected hydroxyl group and a fluorine substituent, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Acts as a core structure for creating novel organic electronic materials due to its aromaticity and functional group versatility.
• Dye & Pigment Manufacturing: Serves as an intermediate for producing specialized azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to construct complex nitrogen-containing heterocycles.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-(Benzyloxy)-4-Fluoroaniline
CAS No.	159471-73-5
Molecular Formula	C₁₃H₁₂FNO
Molecular Weight	217.24 g/mol
Synonyms	4-Fluoro-2-(phenylmethoxy)aniline; 2-(Benzyloxy)-4-fluoroaniline; 4-Fluoro-2-benzyloxyaniline; Benzenemethanamine, 4-fluoro-2-(phenylmethoxy)-; 2-Benzyloxy-4-fluoroaniline; 4-Fluoro-2-(benzyloxy)benzenamine; 2-(Benzyloxy)-4-fluoro-benzenamine
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-4-Fluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for fine chemical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.