Description

4-Bromo-2-Fluoro-3-(Trifluoromethyl)Aniline, also known as 4-Bromo-Alpha,Alpha,Alpha,2-Tetrafluoro-m-Toluidine, is a high-value, multi-halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromo, fluoro, and trifluoromethyl substituents, enables precise molecular tuning for developing compounds with enhanced biological activity and material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to innovate in drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups improve metabolic stability and lipophilicity.
• Liquid Crystal & OLED Material Precursor: Employed in the research and production of advanced electronic materials for displays and lighting due to its halogenated aromatic core.
• Organic Synthesis Building Block: Facilitates cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions for creating complex, fluorinated molecular architectures.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized halogenated dyes and pigments with unique color fastness and properties.

Basic Information

Product Name	4-Bromo-2-Fluoro-3-(Trifluoromethyl)Aniline
CAS No.	159329-03-0
Molecular Formula	C7H4BrF4N
Molecular Weight	258.01 g/mol
Synonyms	4-Bromo-2-fluoro-3-(trifluoromethyl)benzenamine; 4-Bromo-α,α,α,2-tetrafluoro-m-toluidine; 3-Amino-4-bromo-2-fluorobenzotrifluoride; 2-Fluoro-4-bromo-3-(trifluoromethyl)aniline; Benzenamine, 4-bromo-2-fluoro-3-(trifluoromethyl)-; 4-Bromo-2-fluoro-3-trifluoromethylaniline; m-Toluidine, 4-bromo-α,α,α,2-tetrafluoro-
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-3-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.