Description

Ethanone, 1-(2-Amino-4-Fluorophenyl)- (9Ci) is a specialized aromatic ketone building block featuring both amino and fluoro substituents, which are critical functional groups for fine chemical synthesis. This compound matters because it serves as a versatile and high-value intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors who require high-purity, structurally precise intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-cancer agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorescent Dye and Pigment Manufacturing: The aromatic amine and ketone functionalities make it suitable for synthesizing specialized fluorophores and high-performance pigments.
• Academic and Industrial R&D: Employed in research laboratories for method development and exploring new chemical entities (NCEs) in medicinal chemistry.
• Material Science: Potential building block for organic semiconductors and polymers due to its conjugated system and functional handles for further modification.

Basic Information

Product Name	Ethanone, 1-(2-Amino-4-Fluorophenyl)- (9Ci)
CAS No.	159305-15-4
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	2'-Amino-4'-fluoroacetophenone; 1-(2-Amino-4-fluorophenyl)ethanone; 4'-Fluoro-2'-aminoacetophenone; 2-Amino-4-fluoroacetophenone; 4-Fluoro-2-aminoacetophenone; 1-Acetyl-2-amino-4-fluorobenzene; 159305-15-4
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Amino-4-Fluorophenyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.