Description

L-N6-(1-Iminoethyl)Lysine Dihydrochloride is a high-purity, biologically active derivative of the amino acid L-lysine, specifically modified at the ε-amino group. This compound is a critical research-grade chemical, primarily valued as a potent and selective inhibitor of nitric oxide synthase (NOS) isoforms, particularly inducible NOS (iNOS). It is an essential tool for researchers and developers in the pharmaceutical and life sciences sectors, enabling the study of nitric oxide signaling pathways, inflammation, and cardiovascular function. The product is supplied as a dihydrochloride salt to enhance its stability and solubility for experimental use.

Application

• Biochemical Research: A key reagent for studying the role of nitric oxide (NO) in cellular signaling, inflammation, and immune response pathways.
• Pharmaceutical Development: Used in preclinical research to investigate novel therapeutic targets for conditions involving dysregulated NO production, such as septic shock, arthritis, and neurodegenerative diseases.
• Enzyme Inhibition Studies: Serves as a standard selective inhibitor for inducible Nitric Oxide Synthase (iNOS) in enzymatic assays and kinetic studies.
• Cell Culture & In Vitro Models: Applied in cell-based assays to modulate NO levels and assess downstream effects on gene expression, apoptosis, and cell viability.
• Academic Research: Utilized in university and institutional labs for fundamental research in biochemistry, physiology, and pharmacology.
• Diagnostic Kit Development: May be incorporated into assay kits designed to measure NOS activity or screen for NOS inhibitors.

Basic Information

Product Name	L-N6-(1-Iminoethyl)Lysine Dihydrochloride
CAS No.	159190-45-1
Molecular Formula	C8H19N3O2 • 2HCl
Molecular Weight	270.18 g/mol (free base: 189.26 g/mol)
Synonyms	L-N6-(1-Iminoethyl)lysine dihydrochloride; N6-(1-Iminoethyl)-L-lysine dihydrochloride; L-NIL dihydrochloride; NIL Dihydrochloride; (S)-2-Amino-6-(1-iminoethylamino)hexanoic acid dihydrochloride; iNOS Inhibitor II; Nitric Oxide Synthase Inhibitor; 159190-45-1
EINECS	Contact for details

Quality Control

Our L-N6-(1-Iminoethyl)Lysine Dihydrochloride is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to meet general reagent-grade standards, specifications can be aligned with specific research requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.