Description

H-Pro-His-Cys-Lys-Arg-Met-Oh is a synthetic hexapeptide sequence containing a unique combination of amino acids, including proline, histidine, cysteine, lysine, arginine, and methionine. This specific sequence is of significant interest in biochemical research and pharmaceutical development due to its potential role in studying enzyme-substrate interactions, metal ion binding, and redox-active peptide systems. It serves as a critical building block for researchers and manufacturers in the life sciences sector. The compound is identified by CAS No. 159147-88-3.

Application

• Biochemical Research: Used as a model peptide for studying protein folding, enzyme kinetics, and molecular recognition processes.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of novel therapeutic peptides and peptidomimetics.
• Proteomics & Diagnostics: Employed in the development of assays, biomarkers, and diagnostic tools that target specific peptide sequences.
• Enzyme Substrate Studies: Acts as a substrate or inhibitor in research focused on proteases, kinases, and other enzymes.
• Metal Chelation Studies: Utilized to investigate the binding affinity and properties of peptides with metal ions like zinc or copper, given the presence of histidine and cysteine residues.
• Peptide Library Synthesis: A component in the construction of combinatorial peptide libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	H-Pro-His-Cys-Lys-Arg-Met-Oh
CAS No.	159147-88-3
Molecular Formula	C32H56N14O8S2
Molecular Weight	829.02 g/mol
Synonyms	Pro-His-Cys-Lys-Arg-Met; H-Pro-His-Cys-Lys-Arg-Met-OH; Hexapeptide P-H-C-K-R-M; Proline-Histidine-Cysteine-Lysine-Arginine-Methionine; PHCKRM; L-Prolyl-L-histidyl-L-cysteinyl-L-lysyl-L-arginyl-L-methionine; (Sequence: Pro-His-Cys-Lys-Arg-Met)
EINECS	Contact for details

Quality Control

Our peptide products are manufactured under strict quality management systems. Each batch of H-Pro-His-Cys-Lys-Arg-Met-Oh undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to store under an inert atmosphere such as argon or nitrogen. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Amino Acid Analysis)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.