Description

Ras Inhibitory Peptide CAS NO 159088-48-9 is a synthetic, cell-permeable peptide designed to specifically inhibit the activity of Ras proteins by competitively binding to their effector domains. This compound is a critical research tool for investigating the oncogenic signaling pathways driven by mutated Ras, a key driver in a significant percentage of human cancers. It is primarily utilized by researchers and pharmaceutical developers in oncology, cell biology, and drug discovery to study signal transduction mechanisms and validate novel therapeutic targets.

Application

• Biochemical Research: Used as a specific inhibitor to dissect the Ras/Raf/MEK/ERK signaling cascade in in vitro assays.
• Cell-Based Studies: Employed to inhibit Ras-dependent processes, such as proliferation and differentiation, in cultured cell lines to establish phenotypic causality.
• Target Validation: Serves as a critical proof-of-concept tool in early-stage oncology drug discovery programs to confirm the therapeutic potential of targeting Ras pathways.
• Mechanistic Investigation: Facilitates the study of Ras isoform-specific functions (H-Ras, N-Ras, K-Ras) and their roles in various cancer types.
• Standard & Control: Acts as a reference standard or positive control in high-throughput screening (HTS) campaigns designed to identify novel Ras inhibitors.

Basic Information

Product Name	Ras Inhibitory Peptide
CAS No.	159088-48-9
Molecular Formula	C34H59N11O9S
Molecular Weight	797.97 g/mol
Synonyms	Ras Inhibitor Peptide; Ras Inhibitory Peptide (RIP); FTY720 S-Phosphate; Fingolimod Phosphate; (2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol Dihydrogen Phosphate Ester); S-Fingolimod Phosphate; FTY720-P; 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol 1-(Dihydrogen Phosphate)
EINECS	Contact for details

Quality Control

Our Ras Inhibitory Peptide is manufactured under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure consistency and reliability. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.