Description

Aspartyl-Tyrosyl-Phosphomethionyl-Aspartyl-Methionyl-Lysine CAS NO 158999-11-2 is a synthetic, phosphorylated hexapeptide sequence of significant interest in biochemical and pharmaceutical research. This compound is valued for its role as a highly specific substrate or inhibitor in studies of protein kinases, phosphatases, and other enzymes involved in critical cellular signaling pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in drug discovery and proteomics.

Application

• Biochemical Research: As a specific substrate for studying the activity and kinetics of tyrosine or serine/threonine kinases.
• Drug Discovery: Screening and validation of novel therapeutic compounds targeting phosphorylation-dependent diseases.
• Enzyme Characterization: Investigating the specificity and mechanism of action of phosphatases and other regulatory enzymes.
• Proteomics & Signal Transduction Studies: A tool for mapping and understanding complex intracellular signaling networks.
• Diagnostic Assay Development: Potential use in developing high-sensitivity assays for kinase activity in clinical samples.
• Academic Research: Fundamental studies in cell biology, oncology, and neurology related to phosphorylation events.

Basic Information

Product Name	Aspartyl-Tyrosyl-Phosphomethionyl-Aspartyl-Methionyl-Lysine
CAS No.	158999-11-2
Molecular Formula	C38H60N9O19PS2
Molecular Weight	1049.06 g/mol
Synonyms	Asp-Tyr-pMet-Asp-Met-Lys; pMet Hexapeptide; Phosphomethionine-containing Peptide; H-Asp-Tyr-pMet-Asp-Met-Lys-OH; Asp-Tyr-phosphoMet-Asp-Met-Lys; Substrate for Met Kinase; Research Peptide 158999-11-2; Custom Phosphopeptide
EINECS	Contact for details

Quality Control

Our research-grade peptides are produced under stringent conditions to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and mass spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing purity, amino acid analysis, and other relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.