Description

5-Pyrimidinecarboxylicacid,2-Amino-1,4,5,6-Tetrahydro-(9Ci) is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 158832-73-6. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular scaffolds. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Employed in the development and optimization of scalable synthetic routes for commercial API manufacturing.
• Bioconjugation & Probe Development: The carboxylic acid and amino functional groups make it suitable for creating labeled compounds and biochemical probes.

Basic Information

Product Name	5-Pyrimidinecarboxylicacid,2-Amino-1,4,5,6-Tetrahydro-(9Ci)
CAS No.	158832-73-6
Molecular Formula	C5H7N3O2
Molecular Weight	141.13 g/mol
Synonyms	2-Amino-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid; 2-Amino-5-carboxy-1,4,5,6-tetrahydropyrimidine; 5-Pyrimidinecarboxylic acid, 2-amino-1,4,5,6-tetrahydro-; 2-Aminotetrahydropyrimidine-5-carboxylic acid; 158832-73-6; 2-Amino-5-carboxy-tetrahydropyrimidine
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxylicacid,2-Amino-1,4,5,6-Tetrahydro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), impurity profile, and residual solvents are provided and available upon request. We adhere to cGMP principles for pharmaceutical intermediates to support our clients' regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.