Description

R-Tirofiban is a potent and selective non-peptide antagonist of the platelet glycoprotein IIb/IIIa receptor, a key target in antiplatelet therapy. This high-purity active pharmaceutical ingredient (API) is critical for the development and manufacturing of pharmaceutical formulations aimed at preventing thrombotic complications. It is primarily utilized by pharmaceutical companies and research institutions engaged in cardiovascular drug development, clinical research, and analytical standard preparation.

Application

• Pharmaceutical API: Primary active ingredient in the formulation of antiplatelet injectable drugs.
• Clinical Research: Used in studies investigating new therapeutic protocols for acute coronary syndromes and percutaneous coronary interventions (PCI).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Biochemical Research: Tool compound for studying platelet aggregation mechanisms and glycoprotein IIb/IIIa receptor function in vitro.
• Drug Development: Key intermediate in the R&D of novel anti-thrombotic agents and combination therapies.

Basic Information

Product Name	R-Tirofiban
CAS No.	158808-86-7
Molecular Formula	C22H36N2O5S
Molecular Weight	440.60 g/mol
Synonyms	Tirofiban Hydrochloride (R-enantiomer); (R)-Tirofiban; L-700,462; MK-383 (R-form); N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine; Aggrastat (active enantiomer); GP IIb/IIIa Inhibitor (R-enantiomer)
EINECS	Contact for details

Quality Control

Our R-Tirofiban CAS NO 158808-86-7 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high-grade pharmaceutical standards. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided to support regulatory submissions and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and protected from light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.