Description

2-Phenyl-6-Trifluoromethyl-Pyrimidin-4-Ol is a versatile pyrimidine derivative characterized by its phenyl and trifluoromethyl substituents, offering unique electronic and steric properties. This compound is a critical building block in advanced organic synthesis, valued for its role in modulating the biological activity and physicochemical profile of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new drug candidates, particularly for kinase inhibitors, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Material Science: Acts as a precursor for functionalized ligands in catalysis or as a monomer for specialty polymers with specific electronic characteristics.
• Chemical Biology: Employed as a molecular probe or scaffold in the study of enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis: Provides a foundational structure for contract research organizations (CROs) and fine chemical companies to build complex, tailor-made molecules for client projects.

Basic Information

Product Name	2-Phenyl-6-Trifluoromethyl-Pyrimidin-4-Ol
CAS No.	158715-14-1
Molecular Formula	C11H7F3N2O
Molecular Weight	240.18 g/mol
Synonyms	4-Hydroxy-2-phenyl-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-2-phenylpyrimidin-4-ol; 2-Phenyl-6-(trifluoromethyl)-4-pyrimidinol; 4-Pyrimidinol, 2-phenyl-6-(trifluoromethyl)-; 158715-14-1; 2-Phenyl-6-trifluoromethyl-4-pyrimidinol
EINECS	Contact for details

Quality Control

Our 2-Phenyl-6-Trifluoromethyl-Pyrimidin-4-Ol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and a Certificate of Analysis (COA) with every shipment to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.