Description

5-(Difluorosulfomethyl)Uracil is a specialized fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both uracil and difluorosulfomethyl moieties, makes it a valuable precursor for developing novel pharmaceuticals and agrochemicals. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate fluorinated motifs into active compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of novel antiviral and anticancer agents, leveraging the uracil scaffold.
• Agrochemical Synthesis: Used in creating advanced, high-performance pesticides and herbicides where fluorination enhances biological activity and stability.
• Fluorinated Building Block: Serves as a versatile precursor in medicinal chemistry for introducing the difluorosulfomethyl group into target molecules.
• Nucleoside Analogue Research: Fundamental material in the synthesis of modified nucleosides for biochemical and therapeutic studies.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing of complex, value-added specialty chemicals.

Basic Information

Product Name	5-(Difluorosulfomethyl)Uracil
CAS No.	158698-42-1
Molecular Formula	C5H4F2N2O3S
Molecular Weight	210.16 g/mol
Synonyms	5-(Difluoromethylsulfonyl)uracil; 5-(Difluoromethanesulfonyl)uracil; 2,4(1H,3H)-Pyrimidinedione, 5-[(difluoromethyl)sulfonyl]-; Uracil, 5-(difluorosulfomethyl)-; 5-[(Difluoromethyl)sulfonyl]pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5-(Difluorosulfomethyl)Uracil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.