Description

1,2-Benzenediol, 4-Ethyl-3-Fluoro- is a fluorinated catechol derivative, a specialized organic intermediate of significant interest in advanced chemical synthesis. Its unique structure, combining the reactive diol moiety with ethyl and fluorine substituents, makes it a valuable building block for creating complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atom can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the creation of specialty monomers for high-performance polymers, such as polycarbonates or epoxy resins, where it can impart unique thermal and chemical resistance.
• Material Science Research: Utilized in the development of advanced organic electronic materials, including charge-transport layers or fluorophores.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial laboratories.

Basic Information

Product Name	1,2-Benzenediol, 4-Ethyl-3-Fluoro-
CAS No.	158641-49-7
Molecular Formula	C8H9FO2
Molecular Weight	156.16 g/mol
Synonyms	4-Ethyl-3-fluorobenzene-1,2-diol; 3-Fluoro-4-ethylcatechol; 4-Ethyl-3-fluoropyrocatechol; 1,2-Dihydroxy-4-ethyl-3-fluorobenzene; 3-Fluoro-4-ethyl-1,2-benzenediol; 4-Ethyl-3-fluoro-1,2-dihydroxybenzene; 3-Fluoro-4-ethylcatechol
EINECS	Contact for details

Quality Control

Our 1,2-Benzenediol, 4-Ethyl-3-Fluoro- is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its nature of being easily oxidized, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.