Description

Bet V Iii Protein CAS NO 158624-02-3 is a purified, well-characterized allergen protein derived from birch pollen. This high-purity reference standard is critical for research and diagnostic applications, enabling precise study and detection of specific allergic responses. It is an essential reagent for immunology research laboratories, diagnostic kit manufacturers, and pharmaceutical companies developing allergy therapeutics and vaccines.

Application

• Immunological Research: Used as a key antigen to study IgE-mediated allergic reactions, epitope mapping, and immune response mechanisms related to birch pollen allergy.
• Diagnostic Assay Development: Serves as a critical component in the development and calibration of in vitro diagnostic (IVD) tests, such as ELISA and ImmunoCAP, for specific allergy testing.
• Allergen Standardization: Acts as a primary reference standard for the quantification and quality control of allergen extracts used in skin prick tests and immunotherapy solutions.
• Vaccine & Therapeutic Development: Employed in preclinical research for the development and evaluation of allergy vaccines (desensitization therapies) and monoclonal antibody treatments.
• Food Safety & Cross-Reactivity Studies: Utilized to investigate cross-reactivity between birch pollen allergens and proteins in certain foods (e.g., apples, carrots) in oral allergy syndrome research.

Basic Information

Product Name	Bet V Iii Protein
CAS No.	158624-02-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Bet v III; Birch Pollen Allergen Bet v III; Bet v 3; Pathogenesis-related protein PR-10; Major pollen allergen Bet v III; Betula verrucosa allergen Bet v III; Allergen Bet v 1.0301 (isoform); Ribonuclease-like allergen
EINECS	Contact for details

Quality Control

Our Bet V Iii Protein is produced under stringent quality management systems. Each batch undergoes comprehensive analytical characterization, including purity assessment by HPLC and identity confirmation by mass spectrometry and immunological activity testing. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Aliquot contents upon receipt to minimize product exposure.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Immunoblot/ELISA)	Positive for Bet v III reactivity
Purity (SDS-PAGE / HPLC)	≥ 90%
Protein Content (BCA/Lowry)	≥ 95% of dry weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (IgE-binding)	Confirmed by ELISA inhibition
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.