Description

L-Ornithine, N2-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is a protected derivative of the amino acid L-ornithine, featuring the fluorenylmethoxycarbonyl (Fmoc) protecting group on its side-chain amine. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins. It is essential for researchers and manufacturers in pharmaceutical development, biotechnology, and life sciences who require high-purity, protected amino acids for the production of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino acid for the sequential construction of peptides on resin.
• Pharmaceutical Intermediates: Used in the research and GMP manufacturing of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a key reagent for introducing the ornithine moiety into biomolecules for labeling or functionalization.
• Biochemical Research: Employed in studies of enzyme substrates, metabolic pathways, and protein structure-function relationships.
• Combinatorial Chemistry: Utilized in libraries for drug discovery and high-throughput screening of bioactive compounds.
• Proteomics & Antibody Development: Acts as a component in the synthesis of specialized peptides for epitope mapping and antibody production.

Basic Information

Product Name	L-Ornithine, N2-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	158599-00-9
Molecular Formula	C20H20N2O5
Molecular Weight	368.38 g/mol
Synonyms	Fmoc-L-ornithine; Fmoc-Orn-OH; Nα-Fmoc-Nδ-Boc-L-ornithine (common protected form); N²-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-ornithine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-aminopentanoic acid; Fmoc-Ornithine; Boc-L-Ornithine(Fmoc)-OH; Fmoc-Orn(Boc)-OH
EINECS	Contact for details

Quality Control

Our L-Ornithine, N2-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and production. Quality is verified through comprehensive analytical testing including HPLC, NMR, and optical rotation. A Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with each batch to support regulatory filings and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.