Description

Alamethicin F50 Pyromellitate is a specialized synthetic peptide derivative, a pyromellitic acid salt of the ion-channel forming peptide alamethicin. This compound is valued for its role as a model system in biophysical and membrane research, providing a consistent and well-characterized tool for studying ion transport mechanisms. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and advanced material science sectors.

Application

• Biophysical Research: As a model ion channel-forming peptide for studying membrane permeability, voltage-gating, and pore formation in lipid bilayers.
• Pharmaceutical Development: Used in the research and screening of novel antibiotics and antimicrobial agents that target microbial membranes.
• Membrane Protein Studies: Serves as a reference standard and tool for calibrating electrophysiology equipment (e.g., patch-clamp setups) and validating experimental systems.
• Drug Delivery Systems: Investigated for its potential in creating synthetic channels or pores for controlled release mechanisms in nanocarrier technologies.
• Bio-sensing: Incorporated into sensor platforms for the detection of ionic fluxes and membrane-disrupting compounds.
• Academic & Industrial R&D: A critical reagent for fundamental research in biochemistry, cell biology, and supramolecular chemistry.

Basic Information

Product Name	Alamethicin F50 Pyromellitate
CAS No.	158598-06-2
Molecular Formula	C112H167N25O31 • (C10H2O8)x
Molecular Weight	~2200 g/mol (base peptide)
Synonyms	Alamethicin Pyromellitate Salt; Alamethicin F50, Pyromellitic Acid Salt; F50 Alamethicin Pyromellitate; Peptide Ion Channel Model Compound; 1,2,4,5-Benzenetetracarboxylic Acid, Alamethicin Salt; Synthetic Alamethicin Derivative; Membrane Pore-Forming Peptide Salt
EINECS	Contact for details

Quality Control

Our Alamethicin F50 Pyromellitate is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our customers in pharmaceutical and advanced research & development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Total Peptide Content)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Confirmed by membrane conductance assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.