Description

5-Nitro-2-(Trifluoromethoxy)Aniline is a specialized aromatic amine derivative featuring both nitro and trifluoromethoxy functional groups, which confer unique electronic and steric properties. This compound is a critical high-purity intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), valued for its role in introducing specific molecular motifs. It is primarily utilized by pharmaceutical R&D teams, agrochemical manufacturers, and developers of functional dyes and pigments.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a precursor for developing advanced herbicides and pesticides with enhanced efficacy and environmental profiles.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and pigments that require light-fastness and chemical stability.
• Liquid Crystal & OLED Materials: An important intermediate for creating fluorinated components used in electronic display technologies.
• Organic Synthesis & Research: Employed in academic and industrial laboratories for constructing complex molecules in medicinal chemistry and material science projects.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties into polymer chains.

Basic Information

Product Name	5-Nitro-2-(Trifluoromethoxy)Aniline
CAS No.	158579-82-9
Molecular Formula	C7H5F3N2O3
Molecular Weight	222.12 g/mol
Synonyms	2-Amino-4-nitro-1-(trifluoromethoxy)benzene; 2-Trifluoromethoxy-5-nitroaniline; 5-Nitro-2-(trifluoromethoxy)benzenamine; 2-Amino-1-trifluoromethoxy-4-nitrobenzene; 1-Trifluoromethoxy-2-amino-4-nitrobenzene; Benzenamine, 5-nitro-2-(trifluoromethoxy)-; 5-Nitro-α,α,α-trifluoro-o-anisidine
EINECS	Contact for details

Quality Control

Our production of 5-Nitro-2-(Trifluoromethoxy)Aniline adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability. All materials undergo rigorous analytical testing, including HPLC, GC, and NMR, to verify identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specified parameters. We operate under a cGMP-compliant quality management system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.