Description

(1R,2S)-(-)-2-Aminocyclohexanecarboxylic Acid Hydrochloride is a high-purity chiral building block and a hydrochloride salt of a non-proteinogenic amino acid derivative. This compound is critical for the synthesis of complex molecules where precise stereochemistry is required for biological activity or material properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, chiral catalysts, and advanced materials.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic diseases.
• Peptidomimetics & Peptide Synthesis: Used to introduce constrained cyclohexyl scaffolds into peptide backbones to enhance metabolic stability, bioavailability, and conformational rigidity.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Chemical Biology Research: Employed as a tool compound in studying enzyme mechanisms, receptor binding, and as a building block for probe molecules.
• Material Science: Potential monomer for the synthesis of specialized polyamides or other polymers with unique structural properties.

Basic Information

Product Name	(1R,2S)-(-)-2-Aminocyclohexanecarboxylic Acid Hydrochloride
CAS No.	158414-48-3
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	(1R,2S)-2-Aminocyclohexanecarboxylic acid hydrochloride; (-)-cis-2-Aminocyclohexanecarboxylic acid HCl; (1R,2S)-ACHC HCl; cis-2-Aminocyclohexanecarboxylic acid hydrochloride (enantiomer); L-ACHC hydrochloride (ambiguous); (1R,2S)-1-Amino-2-carboxycyclohexane hydrochloride; 2-Aminocyclohexanecarboxylic acid hydrochloride, (1R,2S)-(-)-
EINECS	Contact for details

Quality Control

Our (1R,2S)-(-)-2-Aminocyclohexanecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and chiral excess is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.