Description

2,2,2-Trifluoro-1-(4-Trifluoromethyl-Phenyl)-Ethylamine is a high-value fluorinated aromatic amine building block, prized for its unique trifluoromethyl and trifluoroethyl motifs which impart significant lipophilicity and metabolic stability to target molecules. This compound is essential for advanced research and development in life sciences, enabling the synthesis of novel compounds with enhanced biological activity. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials industries for creating next-generation active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a key precursor for fluorinated components in electronic display materials, improving charge transport and stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with unique surface properties, chemical resistance, and optical characteristics.
• Catalyst & Ligand Development: Utilized in organometallic chemistry to develop novel chiral catalysts and ligands for asymmetric synthesis.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2,2,2-Trifluoro-1-(4-Trifluoromethyl-Phenyl)-Ethylamine
CAS No.	158388-49-9
Molecular Formula	C9H7F6N
Molecular Weight	243.15 g/mol
Synonyms	α-(Trifluoromethyl)-4-(trifluoromethyl)benzeneethanamine; 1-[4-(Trifluoromethyl)phenyl]-2,2,2-trifluoroethanamine; 4-(Trifluoromethyl)-α-(trifluoromethyl)benzeneethanamine; 2,2,2-Trifluoro-1-[4-(trifluoromethyl)phenyl]ethan-1-amine; 1-(4-Trifluoromethylphenyl)-2,2,2-trifluoroethylamine; 4-(Trifluoromethyl)benzyltrifluoroethylamine; (4-Trifluoromethylphenyl)trifluoroethylamine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(4-Trifluoromethyl-Phenyl)-Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality ensures the material is suitable for demanding applications in pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali nature, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.