Description

Cloxazolam is a synthetic benzodiazepine derivative, a class of compounds known for their potent pharmacological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and advanced research institutions engaged in neuropharmacology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in preclinical and clinical research for studying GABA-A receptor modulators and their therapeutic potential.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Chemical Synthesis: Employed in organic synthesis for the preparation of more complex molecules with targeted pharmacological profiles.

Basic Information

Product Name	Cloxazolam
CAS No.	158251-60-6
Molecular Formula	C17H14ClN3O2
Molecular Weight	327.76 g/mol
Synonyms	10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one; Cloxazolamum; CS-370; OZ-370; Abbott-370; 10-Chloro-11b-(2-chlorophenyl)-2,3,5,7,11b-hexahydro[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
EINECS	Contact for details

Quality Control

Our Cloxazolam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and GC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.