Description

Cloxazolam is a potent benzodiazepine derivative, recognized for its specific pharmacological profile. This compound is of significant interest in advanced pharmaceutical research and development, particularly for neurological studies. It serves as a critical intermediate or reference standard for researchers and manufacturers in the pharmaceutical and life sciences sectors requiring high-purity, well-characterized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: Primary use as a key intermediate or reference standard in the synthesis and study of novel benzodiazepine-class therapeutics.
• Analytical Reference Material: Serves as a high-purity standard for method development and validation in quality control (QC) laboratories using HPLC, GC, or LC-MS.
• Preclinical Studies: Utilized in pharmacological and toxicological research to investigate mechanisms of action, metabolism, and safety profiles.
• Chemical Synthesis: Acts as a specialized building block for medicinal chemists exploring new chemical entities within the benzodiazepine structural class.
• Regulatory Compliance & Documentation: Used to prepare certified reference materials (CRMs) for regulatory submissions and dossier preparation.

Basic Information

Product Name	Cloxazolam
CAS No.	158251-57-1
Molecular Formula	C17H14ClN3O3
Molecular Weight	343.76 g/mol
Synonyms	10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one; Cloxazolamum; Cloxazolam (USAN); Abbott-44090; OZP-5806; CS-370; Oxazolam Derivative
EINECS	Contact for details

Quality Control

Our Cloxazolam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via advanced chromatographic techniques. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical intermediates and can accommodate custom purity requirements for research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.