Description

Carbobenzyloxy-L-Leucyl-L-Serinamide is a protected dipeptide derivative, specifically a Cbz-protected leucine-serinamide. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes. Its defined structure ensures high purity and reproducibility in complex synthetic sequences.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential addition of amino acids in the synthesis of custom peptides.
• Pharmaceutical Research & Development: Used in the discovery and development of peptide-based drugs targeting various diseases.
• Biochemical Probe Synthesis: Serves as a precursor for creating labeled or modified peptides used in biological studies and diagnostic assays.
• Peptidomimetic Development: Acts as a starting material for designing and synthesizing non-peptide compounds that mimic peptide function.
• Academic Research: Employed in university and institutional labs for studying peptide structure, function, and synthesis methodologies.
• Custom Peptide Service Providers: A fundamental raw material for companies offering bespoke peptide synthesis services.

Basic Information

Product Name	Carbobenzyloxy-L-Leucyl-L-Serinamide
CAS No.	158011-06-4
Molecular Formula	C17H25N3O5
Molecular Weight	351.40 g/mol
Synonyms	Cbz-Leu-Ser-NH2; Z-Leu-Ser-NH2; Nα-Carbobenzyloxy-L-leucyl-L-serinamide; Benzyl N-[(2S)-1-[[(2S)-2-amino-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]carbamate; (S)-2-(((Benzyloxy)carbonyl)amino)-4-methyl-N-((S)-2-amino-2-oxoethyl)pentanamide; CBZ-L-LEUCYL-L-SERINAMIDE; Z-L-Leucyl-L-serinamide
EINECS	Contact for details

Quality Control

Our Carbobenzyloxy-L-Leucyl-L-Serinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications are designed to meet the high standards of pharmaceutical R&D and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.