Description

3-(4-Azidophenyl)Propionyl-D-Tyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-Nh2 is a synthetic, azide-functionalized peptide derivative designed for advanced biochemical research and development. This compound is a critical tool for site-specific bioconjugation and labeling applications, enabling the study of protein interactions and cellular processes. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, proteomics, and the development of novel diagnostic agents.

Application

• Photoaffinity Labeling Probe: Acts as a key reagent in photoaffinity labeling studies to capture and identify transient protein-protein or protein-ligand interactions.
• Bioconjugation & Click Chemistry: The azido group enables efficient, bioorthogonal conjugation via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC) for attaching fluorophores, biotin, or other functional tags.
• Peptide-Based Drug Discovery: Serves as a modified peptide scaffold or intermediate in the design and synthesis of novel therapeutic candidates targeting specific receptors.
• Proteomics Research: Used to develop affinity probes for the enrichment and identification of target proteins in complex biological samples.
• Diagnostic Reagent Development: Incorporated into the design of sensitive and specific assay components for diagnostic platforms.
• Chemical Biology Tool: Facilitates the study of enzyme activity, signal transduction pathways, and other dynamic biological systems through targeted modification.

Basic Information

Product Name	3-(4-Azidophenyl)Propionyl-D-Tyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-Nh2
CAS No.	157702-46-0
Molecular Formula	C66H92N22O15
Molecular Weight	1417.6 g/mol
Synonyms	[Azido-Phe4]Arg8-Vasopressin Antagonist; 3-(4-Azidophenyl)propionyl-D-Tyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-NH2; Azidophenylpropionyl-Vasopressin Antagonist Peptide; AVP Antagonist, [Azido-Phe4]Arg8-; 1-[3-(4-Azidophenyl)propanoyl]-D-Tyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-amide; Azido-AVP Antagonist; Photoactivatable Vasopressin Antagonist
EINECS	Contact for details

Quality Control

Our production of this high-purity peptide adheres to stringent quality protocols. Every batch is characterized using advanced analytical techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results for assay, purity by HPLC, and related substances. We support research and development under quality systems aligned with cGMP principles for non-pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.