Description

Eptifibatide is a synthetic cyclic heptapeptide that functions as a potent and selective antagonist of the platelet glycoprotein IIb/IIIa receptor. This mechanism of action is critical for the prevention of platelet aggregation, making it a valuable active pharmaceutical ingredient (API). It is primarily utilized in the formulation of injectable antithrombotic medications for acute coronary syndrome. Pharmaceutical manufacturers and research institutions globally require high-purity Eptifibatide CAS NO 157630-07-4 to develop and produce life-saving cardiovascular therapies.

Application

• Active Pharmaceutical Ingredient (API) in injectable antithrombotic drugs.
• Cardiovascular Therapeutics for the management of acute coronary syndrome (ACS), including unstable angina and non-ST-elevation myocardial infarction (NSTEMI).
• Percutaneous Coronary Intervention (PCI) adjunct therapy to prevent ischemic complications during procedures like angioplasty.
• Pharmaceutical Research & Development for studying platelet aggregation inhibitors and developing new cardiovascular formulations.
• Reference Standard in analytical laboratories for quality control and method validation of finished drug products.
• Bulk Drug Substance for contract manufacturing organizations (CMOs) producing sterile injectable dosage forms.

Basic Information

Item	Details
Product Name	Eptifibatide
CAS No.	157630-07-4
Molecular Formula	C35H49N11O9S2
Molecular Weight	831.96 g/mol
Synonyms	Integrilin (Brand Name); Eptifibatide Acetate; MK-0852; N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic (1→6)-disulfide; L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-disulfide; GP IIb/IIIa Inhibitor
EINECS	Contact for details

Quality Control

Our Eptifibatide is manufactured under strict quality systems suitable for pharmaceutical applications. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, aligning with ICH guidelines and current Good Manufacturing Practices (cGMP). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical parameters such as assay, related substances, residual solvents, and microbiological quality.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 10 EU/mg
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/ USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.