Description

n-α-Benzoyl-(ε-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-Yl))Lysyl-Alanyl-Tryptophyl-Phenylalanyl-Prolyl-Prolyl-Norleucinamide is a specialized, high-purity synthetic peptide derivative designed for advanced research and development applications. This compound is valued for its role as a fluorescently labeled substrate or probe, enabling critical studies in enzymology and cellular processes. It is primarily utilized by researchers in the pharmaceutical, biotechnology, and life sciences sectors for protease activity assays, enzyme kinetics, and high-throughput screening.

Application

• Protease and Enzyme Research: Acts as a sensitive, fluorescently tagged substrate for studying the activity, specificity, and inhibition of various proteolytic enzymes.
• High-Throughput Screening (HTS): Employed in automated drug discovery platforms to identify and characterize novel enzyme inhibitors or activators.
• Biochemical Assay Development: Serves as a key component in developing and validating quantitative assays for enzyme kinetics and mechanistic studies.
• Cell Biology Studies: Used as a molecular probe to investigate intracellular protease activity and localization in live or fixed cells.
• Diagnostic Reagent Formulation: Incorporated into diagnostic kits for the detection and measurement of specific protease biomarkers.
• Peptidomimetic & Drug Design: Provides a structural scaffold for designing and testing new peptide-based therapeutic agents.

Basic Information

Product Name	n-α-Benzoyl-(ε-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-Yl))Lysyl-Alanyl-Tryptophyl-Phenylalanyl-Prolyl-Prolyl-Norleucinamide
CAS No.	157610-41-8
Molecular Formula	C58H68N12O12
Molecular Weight	1101.23 g/mol
Synonyms	Bz-K(Abz)-A-W-F-P-P-Nle-NH2; N-Benzoyl-Lys(Abz)-Ala-Trp-Phe-Pro-Pro-Nle-NH2; Abz-K-A-W-F-P-P-Nle-NH2; Fluorescent Peptide Substrate 157610-41-8; N-α-Benzoyl-N-ε-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-L-lysyl-L-alanyl-L-tryptophyl-L-phenylalanyl-L-prolyl-L-prolyl-L-norleucinamide; NBD-labeled Peptide Substrate; Benzoyl-Lys(Abz)-Ala-Trp-Phe-Pro-Pro-Nle-amide
EINECS	Contact for details

Quality Control

Our n-α-Benzoyl-(ε-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-Yl))Lysyl-Alanyl-Tryptophyl-Phenylalanyl-Prolyl-Prolyl-Norleucinamide is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive applications. All batches undergo comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.