Description

4-Fluoro-2-Methoxybenzyl Alcohol is a versatile fluorinated aromatic building block of significant importance in modern synthetic chemistry. Its molecular structure, featuring both a fluorine atom and a methoxy group, makes it a critical intermediate for the development of advanced pharmaceuticals and agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with tailored biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated benzyl alcohol moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances bioavailability and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the synthesis of novel organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create biaryl structures.
• Protecting Group Chemistry: The benzyl alcohol group can be utilized in protective group strategies during multi-step synthetic sequences.
• Fluorine-18 Radiochemistry: Potential precursor for the synthesis of PET (Positron Emission Tomography) tracers in medical imaging.
• Fine Chemical Research: Used in academic and industrial laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	4-Fluoro-2-Methoxybenzyl Alcohol
CAS No.	157068-03-6
Molecular Formula	C8H9FO2
Molecular Weight	156.15 g/mol
Synonyms	(4-Fluoro-2-methoxyphenyl)methanol; 2-Methoxy-4-fluorobenzyl alcohol; 4-Fluoro-2-methoxybenzenemethanol; 4-Fluoro-o-anisyl alcohol; 1-(Hydroxymethyl)-4-fluoro-2-methoxybenzene; 4-Fluoro-2-methoxy-phenylmethanol; α-Hydroxy-4-fluoro-2-methoxytoluene
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methoxybenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.