Description

S-Methyl-L-Thiocitrulline is a specialized, high-purity biochemical reagent and a potent, selective inhibitor of nitric oxide synthase (NOS). This compound matters for researchers and manufacturers requiring precise modulation of nitric oxide pathways in biological systems. It is primarily needed by the pharmaceutical, biotechnology, and life science research sectors for drug discovery, biochemical research, and the development of therapeutic agents targeting cardiovascular and neurological conditions.

Application

• Pharmaceutical Research & Development: As a key biochemical tool for studying the role of nitric oxide synthase (NOS) isoforms in disease models.
• Drug Discovery: Used in high-throughput screening and lead optimization for developing NOS-targeted therapeutics for conditions like sepsis, inflammation, and neurodegeneration.
• Biochemical Assay Standard: Serves as a reference standard and critical reagent in enzymatic assays to measure NOS activity and inhibition.
• Academic & Institutional Research: Essential for basic science investigations into vascular biology, immunology, and cell signaling pathways.
• Preclinical Studies: Utilized in animal models to validate therapeutic hypotheses related to nitric oxide modulation.

Basic Information

Item	Details
Product Name	S-Methyl-L-Thiocitrulline
CAS No.	156719-41-4
Molecular Formula	C7H15N3O2S
Molecular Weight	205.28 g/mol
Synonyms	S-Methyl-L-thiocitrulline; L-Thiocitrulline, S-methyl-; (2S)-2-Amino-5-[(methylsulfanyl)amino]-5-oxopentanoic acid; S-Methylthiocitrulline; NOS Inhibitor; Nitric Oxide Synthase Inhibitor; 156719-41-4
EINECS	Contact for details

Quality Control

Our S-Methyl-L-Thiocitrulline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high-purity standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range available on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.