Description

Toxin 1, Centruroides Limpidus Limpidus is a highly purified, biologically active peptide toxin isolated from the venom of the Mexican scorpion Centruroides limpidus limpidus. This compound is of significant value for its specific and potent modulation of voltage-gated sodium channels (Nav), making it a critical tool for neurological and pharmacological research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on ion channel studies, neurotoxin research, and the development of novel therapeutic agents.

Application

• Neuroscience Research: As a selective sodium channel modulator for studying channel function, gating mechanisms, and neuronal excitability.
• Pharmacological Assay Development: Used as a reference standard or active component in high-throughput screening (HTS) assays for drug discovery targeting ion channels.
• Toxin-Antitoxin Studies: Serves as a key antigen in the development and validation of antivenoms and specific diagnostic antibodies.
• Biochemical Standard: Provides a precise molecular tool for calibrating analytical equipment and validating experimental methods in proteomics and toxicology.
• Academic & Industrial R&D: Fundamental research into peptide structure-activity relationships (SAR) and the design of novel bio-inspired compounds.

Basic Information

Product Name	Toxin 1, Centruroides Limpidus Limpidus
CAS No.	156680-24-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cll1 Toxin; Centruroides limpidus limpidus Toxin 1; Nav Channel Toxin Cll1; Scorpion Toxin Cll1; β-toxin Cll1; Voltage-gated sodium channel toxin 1 (Centruroides limpidus limpidus)
EINECS	Contact for details

Quality Control

Our Toxin 1, Centruroides Limpidus Limpidus is produced and handled under strict quality protocols to ensure batch-to-batch consistency and biological activity. Each lot is characterized using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and bioactivity data, is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	Confirmed by assay
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.