Description

Dde-Lys(Fmoc)-Oh is a specialized, orthogonally protected amino acid derivative essential for advanced peptide synthesis. Its core value lies in enabling complex, multi-step solid-phase peptide synthesis (SPPS) by providing selective deprotection strategies, which is critical for constructing challenging peptide sequences. This compound is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled, sequential assembly of peptides, particularly those requiring orthogonal protection schemes.
• Pharmaceutical Research: Used in the research and development of novel peptide drugs, including anticancer agents, hormones, and antimicrobial peptides.
• Bioconjugation: Serves as a linker or intermediate for attaching peptides to other molecules, surfaces, or carriers in drug delivery system development.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive peptide leads.
• Chemical Biology Studies: Utilized to synthesize labeled or modified peptides for probing protein-protein interactions and enzyme mechanisms.
• Production of Custom Peptides: A critical reagent for CROs (Contract Research Organizations) and CDMOs (Contract Development and Manufacturing Organizations) offering custom peptide synthesis services.

Basic Information

Product Name	Dde-Lys(Fmoc)-Oh
CAS No.	156648-40-7
Molecular Formula	C30H35N3O6
Molecular Weight	533.62 g/mol
Synonyms	Nε-(1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl)-Nα-(9-fluorenylmethoxycarbonyl)-L-lysine; Fmoc-Lys(Dde)-OH; Nα-Fmoc-Nε-Dde-L-lysine; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-6-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino)hexanoic acid; Fmoc-Lys(Dde)-OH CAS 156648-40-7; Fmoc-L-lysine(Dde)-OH; Dde-Lys(Fmoc)-OH
EINECS	Contact for details

Quality Control

Our Dde-Lys(Fmoc)-Oh is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.