Description

Argininosuccinic Acid Disodium Salt is a high-purity biochemical salt of significant importance in advanced research and pharmaceutical development. This compound serves as a critical intermediate and reference standard in the study of the urea cycle and related metabolic pathways. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in metabolic disorder research, enzyme studies, and the development of high-value biochemical reagents.

Application

• Biochemical Research: Used as a key substrate and intermediate in enzymatic studies of the urea cycle, particularly for argininosuccinate lyase and synthetase.
• Diagnostic Reagent Manufacturing: Serves as a critical raw material in the formulation of in-vitro diagnostic (IVD) kits for detecting urea cycle disorders such as argininosuccinic aciduria.
• Pharmaceutical Reference Standard: Employed as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Metabolic Pathway Analysis: Essential for cell culture media and metabolic flux analysis in academic and industrial life science research.
• Enzyme Activity Assays: Acts as a specific substrate in high-throughput screening (HTS) assays to identify modulators of urea cycle enzymes for drug discovery.
• Nutraceutical R&D: Investigated for potential applications in specialized amino acid formulations and metabolic support supplements.

Basic Information

Product Name	Argininosuccinic Acid Disodium Salt
CAS No.	156637-58-0
Molecular Formula	C10H16N4Na2O6
Molecular Weight	350.24 g/mol
Synonyms	L-Argininosuccinic Acid Disodium Salt; Disodium L-Argininosuccinate; Argininosuccinate Disodium Salt; ASA Disodium Salt; N-(L-Arginino)succinic Acid Disodium Salt; (S)-2-(4-Amino-4-carboxybutylamino)-3-carboxypropanoic Acid Disodium Salt; NSC 163040; Argininosuccinic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our Argininosuccinic Acid Disodium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support compliance with relevant guidelines for use as a raw material in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. After opening, ensure the container is resealed immediately under dry atmospheric conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
pH (5% Solution)	6.5 - 8.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.