Description

4-Acetylmethyl-3,4-Dihydro-3-(2,3-Dihydroxypropyl)-2,6-Dimethoxy-5-Nitropyrimidine CAS NO 156360-67-7 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development for targeted therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules, especially those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) for potential therapeutic applications.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the production of specialized APIs for clinical trials and commercial manufacturing.
• Biochemical Research: Employed in studies investigating enzyme inhibition or receptor binding due to its functionalized pyrimidine core.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, low-volume specialty chemicals for advanced applications.

Basic Information

Product Name	4-Acetylmethyl-3,4-Dihydro-3-(2,3-Dihydroxypropyl)-2,6-Dimethoxy-5-Nitropyrimidine
CAS No.	156360-67-7
Molecular Formula	C12H19N3O7
Molecular Weight	317.30 g/mol
Synonyms	5-Nitro-2,6-dimethoxy-3-(2,3-dihydroxypropyl)-3,4-dihydro-4-pyrimidineacetic acid methyl ester; 3-(2,3-Dihydroxypropyl)-2,6-dimethoxy-5-nitro-3,4-dihydro-4-pyrimidineacetic acid methyl ester; Methyl 3-(2,3-dihydroxypropyl)-2,6-dimethoxy-5-nitro-3,4-dihydro-4-pyrimidineacetate; CAS 156360-67-7
EINECS	Contact for details

Quality Control

Our 4-Acetylmethyl-3,4-Dihydro-3-(2,3-Dihydroxypropyl)-2,6-Dimethoxy-5-Nitropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific client protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.