Description

1,6,8-Indolizinetriol, 7-Fluorooctahydro-, 1S-(1.Alpha.,6.Beta.,7.Beta.,8.Beta.,8A.Beta.)- is a complex, stereochemically defined fluorinated indolizine derivative, representing a high-value synthetic intermediate for advanced research and development. This compound matters for its unique molecular architecture, which combines a fluorinated octahydroindolizine core with multiple hydroxyl groups, making it a versatile scaffold for pharmaceutical and agrochemical discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for use in medicinal chemistry programs, structure-activity relationship (SAR) studies, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of potential drug candidates, particularly in neurological and metabolic disease research.
• Medicinal Chemistry Research: Used as a core scaffold for exploring new chemical space and developing novel pharmacophores due to its complex, polyfunctional structure.
• Agrochemical Development: Acts as a precursor in the research and synthesis of new-generation herbicides or fungicides with potentially novel modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study enzyme function or biological pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial-scale production of complex molecules.
• Academic Research: Used in universities and research institutes for methodological studies in asymmetric synthesis and fluorine chemistry.

Basic Information

Product Name	1,6,8-Indolizinetriol, 7-Fluorooctahydro-, 1S-(1.Alpha.,6.Beta.,7.Beta.,8.Beta.,8A.Beta.)-
CAS No.	156150-84-4
Molecular Formula	C10H16FNO3
Molecular Weight	217.24 g/mol
Synonyms	(1S,6S,7S,8S,8aS)-7-Fluorooctahydro-1,6,8-indolizinetriol; 7-Fluoro-1,6,8-trihydroxyoctahydroindolizine (1S,6S,7S,8S,8aS)-; 1S-(1α,6β,7β,8β,8aβ)-7-Fluorooctahydro-1,6,8-indolizinetriol; Fluorinated Octahydroindolizinetriol; CAS 156150-84-4
EINECS	Contact for details

Quality Control

Every batch of 1,6,8-Indolizinetriol, 7-Fluorooctahydro-, 1S-(1.Alpha.,6.Beta.,7.Beta.,8.Beta.,8A.Beta.)- undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality protocols are designed to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing specific batch results for purity, chiral purity, and impurities are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under dry conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.