Description

6,6'-Dithiobis(4-Aminohexanoic Acid) Bis(Trifluoroacetate) is a specialized, high-purity biochemical building block featuring a disulfide bridge and protected amino acid functionalities. This compound is critical for advanced research and development in peptide synthesis and bioconjugation, where precise molecular architecture is required. It is primarily utilized by pharmaceutical R&D teams, peptide manufacturers, and academic researchers focusing on novel therapeutic agents and chemical biology.

Application

• Peptide Synthesis: Serves as a key intermediate for introducing disulfide bonds, which are essential for the structural stability and biological activity of many therapeutic peptides.
• Bioconjugation & Linker Chemistry: Used to create cleavable or reversible cross-links between biomolecules, proteins, and drug payloads in antibody-drug conjugate (ADC) development.
• Chemical Biology Research: A valuable tool for studying protein folding, stability, and function through site-specific disulfide bridge formation.
• Pharmaceutical Intermediates: Acts as a precursor in the synthesis of complex active pharmaceutical ingredients (APIs) that require controlled release or targeted delivery mechanisms.
• Material Science: Potential use in the development of smart polymers and hydrogels with redox-responsive properties.

Basic Information

Product Name	6,6'-Dithiobis(4-Aminohexanoic Acid) Bis(Trifluoroacetate)
CAS No.	156143-51-0
Molecular Formula	C16H24F6N2O8S2
Molecular Weight	574.49 g/mol
Synonyms	6,6'-Dithiodihexanoic Acid Bis(trifluoroacetate); 6-Amino-6'-[(6-amino-6-oxohexyl)dithio]hexanoic Acid Bis(trifluoroacetate); N6,N6'-Bis(trifluoroacetyl)-6,6'-dithiobis(hexanoic acid) Diamine Salt; Disulfide-linked bis(6-aminohexanoic acid) TFA salt; H-Ahx-SS-Ahx-OH•2TFA
EINECS	Contact for details

Quality Control

Our 6,6'-Dithiobis(4-Aminohexanoic Acid) Bis(Trifluoroacetate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.