Description

4-(4-Fluorophenyl)Pyrimidine-2-Thiol is a high-purity, sulfur-containing heterocyclic building block with a fluorinated aromatic substituent. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators leveraging its fluorinated pyrimidine core.
• Material Science Precursor: Serves as a building block for functionalized ligands in catalysis or for creating advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and biochemical tools due to its modifiable thiol and heterocyclic groups.

Basic Information

Product Name	4-(4-Fluorophenyl)Pyrimidine-2-Thiol
CAS No.	155957-43-0
Molecular Formula	C10H7FN2S
Molecular Weight	206.24 g/mol
Synonyms	2-Mercapto-4-(4-fluorophenyl)pyrimidine; 4-(4-Fluorophenyl)-2-pyrimidinethiol; 4-(p-Fluorophenyl)-2-pyrimidinethiol; 2(1H)-Pyrimidinethione, 4-(4-fluorophenyl)-; 4-(4-Fluorophenyl)-2-mercaptopyrimidine; 4-(4-Fluorophenyl)pyrimidine-2-thione
EINECS	Contact for details

Quality Control

Our 4-(4-Fluorophenyl)Pyrimidine-2-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider an inert atmosphere. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.