Description

3-(2,2,2-Trifluoroethoxy)Benzaldehyde is a high-purity fluorinated aromatic aldehyde building block, identified by CAS NO 155908-58-0. This compound is valued for its unique trifluoroethoxy substituent, which imparts enhanced lipophilicity and metabolic stability to target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use as a critical intermediate in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for improved bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoroethoxy group can enhance activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials for displays and lighting applications.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent to introduce aromatic and fluorinated ether functionalities into specialty polymers.
• Chemical Research & Development: A versatile building block for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical manufacturers for use in client-specific, multi-step synthetic routes.

Basic Information

Item	Details
Product Name	3-(2,2,2-Trifluoroethoxy)Benzaldehyde
CAS No.	155908-58-0
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3-(2,2,2-Trifluoroethoxy)benzaldehyde; m-(Trifluoroethoxy)benzaldehyde; 3-Trifluoroethoxybenzaldehyde; Benzaldehyde, 3-(2,2,2-trifluoroethoxy)-; 155908-58-0; 3-(Trifluoroethoxyl)benzaldehyde; 3-(β,β,β-Trifluoroethoxy)benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 3-(2,2,2-Trifluoroethoxy)Benzaldehyde is manufactured and tested under a strict quality management system. We ensure the product meets high-purity standards suitable for research and industrial synthesis. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) documenting all test results is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.