Description

2,5-Difluoro-4-Iodoaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring iodine and fluorine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in fluorinated and iodinated compounds for oncology and CNS therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic cores in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating specialized chemical libraries.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized halogenated dyes and pigments with unique color properties and lightfastness.

Basic Information

Product Name	2,5-Difluoro-4-Iodoaniline
CAS No.	155906-13-1
Molecular Formula	C6H4F2IN
Molecular Weight	254.99 g/mol
Synonyms	4-Iodo-2,5-difluoroaniline; 2,5-Difluoro-4-iodobenzenamine; 1-Amino-2,5-difluoro-4-iodobenzene; Benzenamine, 2,5-difluoro-4-iodo-; 4-Iodo-2,5-difluoro-phenylamine; 2,5-Difluoro-4-iodoaniline; 155906-13-1; 2,5-Difluoro-4-iodo-aniline
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-Iodoaniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Total impurities < 2.0%
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.