Description

Bistramide D CAS NO 155660-91-6 is a potent, naturally occurring marine-derived compound belonging to the bistramide class of polyketide macrolides. This molecule is of significant interest in biochemical and pharmacological research due to its unique mechanism of action as a highly selective modulator of actin cytoskeleton dynamics. It is primarily sought after by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in advanced cell biology studies, cancer research, and the development of novel therapeutic agents targeting cellular architecture and motility.

Application

• Biochemical Research: Used as a precise molecular tool to study actin polymerization/depolymerization dynamics and their role in cellular processes.
• Oncology Research: Investigated for its potential anti-cancer properties by disrupting the cytoskeleton of tumor cells, affecting cell division and migration.
• Cell Biology Studies: Applied in vitro to explore fundamental mechanisms of cell motility, shape change, and intracellular transport.
• Pharmaceutical Development: Serves as a lead compound or a chemical probe in drug discovery programs focused on cytoskeletal targets.
• Neuroscience Research: Utilized to examine the role of actin in neuronal growth cone guidance and synaptic plasticity.
• Toxicology Studies: Employed to understand the cellular response to cytoskeletal disruption.

Basic Information

Product Name	Bistramide D
CAS No.	155660-91-6
Molecular Formula	C₄₇H₇₉N₃O₁₀
Molecular Weight	846.2 g/mol
Synonyms	Bistramide D; Bistramide D (Lissoclinum bistratum); Bistramide D, Lissoclinum bistratum; (3S,4S,5S,6R,7S,9S,11S,12R,13S,14E,16E,18E,20S,21R,24S,26R,27S,29S,31S,33R,35S,36S)-33-[(2S,3S,4S,5R,6R)-4,5-Dihydroxy-6-methyl-3-(methylamino)oxan-2-yl]oxy-5,9,27,29,31-pentahydroxy-4,6,11,13,20,24,26,35-octamethyl-3,7,12,21,36-pentaoxo-1-oxa-2,8,10,22,25,34-hexaazacyclohexatriaconta-14,16,18-triene-36-carboxamide
EINECS	Contact for details

Quality Control

Our Bistramide D is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and structural verification via NMR and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, methanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.