Description

Tremacamra is a synthetic, low-molecular-weight compound with significant biological activity, identified by the CAS registry number 155576-45-7. This compound is valued for its targeted mechanism of action, making it a critical intermediate and research tool in advanced therapeutic development. It is primarily utilized by pharmaceutical R&D teams and biotechnology companies engaged in the discovery of novel anti-inflammatory and immunomodulatory agents.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel therapeutic candidates.
• Immunology Studies: Used as a research tool to investigate specific pathways involved in inflammatory and autoimmune responses.
• Biochemical Assay Development: Employed as a standard or inhibitor in high-throughput screening (HTS) and in vitro diagnostic assay development.
• Preclinical Drug Discovery: Acts as a lead compound or pharmacophore model for structure-activity relationship (SAR) studies in medicinal chemistry.
• Academic Research: Utilized in university and institutional labs for fundamental research in cell signaling and molecular biology.
• Contract Manufacturing: Supplied as a high-purity building block for the custom synthesis of more complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Tremacamra
CAS No.	155576-45-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BIRT 377; BIRT-377; LFA-1 Antagonist BIRT 377; (2S)-2-[[[4-[(4-Methylphenyl)sulfonyl]amino]phenyl]acetyl]amino]-3-[4-(2,4,6-trimethylphenyl)thio]phenyl]propanoic Acid; (αS)-α-[[[4-[[(4-Methylphenyl)sulfonyl]amino]phenyl]acetyl]amino]-4-[(2,4,6-trimethylphenyl)thio]benzenepropanoic Acid
EINECS	Contact for details

Quality Control

Our Tremacamra (CAS 155576-45-7) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.