Description

Dermaseptin B CAS NO 155483-06-0 is a cationic antimicrobial peptide (AMP) originally isolated from the skin of arboreal frogs. This compound is of significant interest for its broad-spectrum activity against bacteria, fungi, and other pathogens. It is primarily utilized in advanced research and development within the pharmaceutical, biotechnology, and cosmetic industries for exploring novel therapeutic and preservative applications.

Application

• Antimicrobial Research: Serves as a key model compound in studies investigating the mechanism of action of host-defense peptides against multidrug-resistant bacteria and fungi.
• Pharmaceutical Development: Explored as a lead structure for designing new antibiotic and antifungal agents, particularly for topical formulations.
• Cosmetic & Personal Care: Investigated for potential use as a natural preservative or active ingredient in skincare products targeting microbial imbalances.
• Biomaterial Coating: Research into coating medical devices or implants with Dermaseptin B derivatives to prevent biofilm formation and infections.
• Veterinary Medicine: Studied for applications in animal health, such as in mastitis prevention or wound care treatments.
• Food Safety Research: Potential application explored for developing natural antimicrobial coatings or additives to enhance food preservation.

Basic Information

Product Name	Dermaseptin B
CAS No.	155483-06-0
Molecular Formula	C142H238N44O37
Molecular Weight	3016.6 g/mol
Synonyms	Dermaseptin B; Dermaseptin B2; DRS-B; Antimicrobial peptide Dermaseptin B; Dermaseptin (Phyllomedusa bicolor); [Lys4, Lys20]-Dermaseptin; ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
EINECS	Contact for details

Quality Control

Our Dermaseptin B is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research and development purposes. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. While typically supplied as a research-grade material, production can be aligned with cGMP guidelines for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.