Description

Inogatran CAS NO 155415-08-0 is a synthetic, low molecular weight thrombin inhibitor. This compound is of significant interest in pharmaceutical research and development due to its potent and selective anticoagulant properties. It serves as a key intermediate and active pharmaceutical ingredient (API) for researchers and manufacturers developing novel antithrombotic therapies targeting cardiovascular diseases and surgical procedures.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of advanced direct thrombin inhibitors (DTIs).
• Anticoagulant Drug Development: Core active component in research for next-generation medications to prevent and treat blood clots (thrombosis).
• Biochemical Research: A standard and selective thrombin inhibitor used in in vitro studies to understand coagulation pathways and enzyme kinetics.
• Diagnostic Reagent Component: Potential use in the formulation of specialized diagnostic kits for monitoring coagulation status.
• Medical Device Coatings: Investigational application for creating biocompatible, anti-thrombogenic surfaces on stents, catheters, and other implants.

Basic Information

Product Name	Inogatran
CAS No.	155415-08-0
Molecular Formula	C23H40N8O6
Molecular Weight	524.62 g/mol
Synonyms	Inogatran; BIBR 1048; (2R,4R)-4-Methyl-1-[N2-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl]-2-piperidinecarboxylic acid; 1-[(3-Methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-arginyl]-4-methyl-cis-2-piperidinecarboxylic acid; BIBR-1048; Dabigatran intermediate; Direct Thrombin Inhibitor intermediate
EINECS	Contact for details

Quality Control

Our Inogatran is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.