Description

1H-Purine-2,6-Dione, 3,7-Dihydro-8-(2-(2-Chloro-3,4-Dimethoxyphenyl)Et Henyl)-1,3,7-Trimethyl-,(E)- CAS NO 155271-45-7 is a high-purity, structurally complex xanthine derivative designed for advanced research and development. This compound is valued for its role as a key synthetic intermediate and pharmacological research tool, particularly in the study of adenosine receptor interactions. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel adenosine receptor antagonists and other purine-based drug candidates.
• Biochemical Research: Used as a reference standard and a tool compound for studying receptor binding, signal transduction pathways, and enzyme inhibition assays.
• Fine Chemical Synthesis: Acts as a versatile building block for the preparation of more complex, functionalized xanthine derivatives with tailored biological activities.
• Academic Research: Employed in universities and research institutes for investigating the structure-activity relationships (SAR) of purine analogues.
• Preclinical Development: Utilized in the early-stage development of potential therapeutics targeting neurological, cardiovascular, and inflammatory conditions.

Basic Information

Product Name	1H-Purine-2,6-Dione, 3,7-Dihydro-8-(2-(2-Chloro-3,4-Dimethoxyphenyl)Et Henyl)-1,3,7-Trimethyl-,(E)-
CAS No.	155271-45-7
Molecular Formula	C₂₀H₂₃ClN₄O₄
Molecular Weight	418.87 g/mol
Synonyms	(E)-8-[2-(2-Chloro-3,4-dimethoxyphenyl)ethenyl]-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione; 8-[(E)-2-(2-Chloro-3,4-dimethoxyphenyl)vinyl]-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione; 1,3,7-Trimethyl-8-[(E)-2-(2-chloro-3,4-dimethoxyphenyl)vinyl]-3,7-dihydro-1H-purine-2,6-dione; Xanthine derivative 155271-45-7; 8-Styrylxanthine derivative; Chloro-dimethoxystyryl-theophylline analogue; Adenosine receptor ligand intermediate.
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using HPLC, NMR, and MS to ensure structural identity and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports its use in GMP-grade synthesis and critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under conditions that minimize exposure to ambient light and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.