Description

2-(9-Fluorenyl)Glycine is a specialized, high-purity amino acid derivative featuring a fluorenyl protecting group, which is critical for advanced peptide synthesis and pharmaceutical research. This compound matters because it serves as a key chiral building block for the development of novel therapeutic peptides and complex organic molecules, ensuring precise stereochemical control. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptide-based drug discovery and process development.

Application

• As a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Intermediate in the research and development of pharmaceutical actives, particularly peptide drugs and enzyme inhibitors.
• Chiral synthon for constructing complex organic molecules and natural product analogs in medicinal chemistry.
• Starting material for the preparation of fluorenylmethyloxycarbonyl (Fmoc) protected peptide fragments.
• Used in biochemical research for studying protein structure and function.
• Key reagent in the synthesis of non-natural amino acids and peptidomimetics for drug design.

Basic Information

Product Name	2-(9-Fluorenyl)Glycine
CAS No.	155172-78-4
Molecular Formula	C₁₅H₁₃NO₂
Molecular Weight	239.27 g/mol
Synonyms	2-(9H-Fluoren-9-yl)glycine; N-(9H-Fluoren-9-yl)glycine; 9-Fluorenylglycine; Fm-Gly-OH; (9H-Fluoren-9-yl)aminoacetic Acid; 2-(Fluoren-9-yl)aminoacetic Acid; 2-[(9H-Fluoren-9-yl)amino]acetic Acid; Glycine, N-(9H-fluoren-9-yl)-
EINECS	Contact for details

Quality Control

Our 2-(9-Fluorenyl)Glycine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.