Description

2-Amino-4-Chloro-6-Pyrrolidin-1-Ylpyrimidine-5-Carbaldehyde is a high-purity pyrimidine derivative building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for exploring new chemical entities and reaction pathways in academic and industrial labs.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development of scalable synthetic routes.

Basic Information

Product Name	2-Amino-4-Chloro-6-Pyrrolidin-1-Ylpyrimidine-5-Carbaldehyde
CAS No.	155087-33-5
Molecular Formula	C9H12ClN5O
Molecular Weight	241.68 g/mol
Synonyms	4-Chloro-2-amino-6-(1-pyrrolidinyl)pyrimidine-5-carboxaldehyde; 2-Amino-4-chloro-6-(pyrrolidin-1-yl)pyrimidine-5-carbaldehyde; 5-Formyl-2-amino-4-chloro-6-pyrrolidin-1-ylpyrimidine; 155087-33-5; 4-Chloro-2-amino-6-pyrrolidin-1-yl-pyrimidine-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Chloro-6-Pyrrolidin-1-Ylpyrimidine-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.