Description

Methyl 4-Aminothieno[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, heterocyclic organic building block of significant importance in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for constructing complex molecular architectures, particularly in the creation of novel kinase inhibitors and other targeted therapeutic agents. It is primarily sought after by research institutions, custom synthesis houses, and pharmaceutical companies engaged in the discovery of new drugs for oncology, inflammatory diseases, and central nervous system disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent and selective kinase inhibitors for cancer therapy.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Employed in the contract manufacturing of Active Pharmaceutical Ingredients (APIs) and advanced intermediates for clinical trials.
• Biochemical Tool Development: Utilized to create probe molecules for studying cellular signaling pathways and enzyme functions.
• Academic Research: Serves as a starting material for novel heterocyclic chemistry and methodology development in university laboratories.

Basic Information

Product Name	Methyl 4-Aminothieno[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	155087-15-3
Molecular Formula	C8H7N3O2S
Molecular Weight	209.22 g/mol
Synonyms	Methyl 4-amino-2,3-dihydrothieno[2,3-d]pyrimidine-6-carboxylate; 4-Aminothieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester; 6-(Methoxycarbonyl)thieno[2,3-d]pyrimidin-4-amine; Methyl 4-aminothieno[2,3-d]pyrimidine-6-carboxylate; Thieno[2,3-d]pyrimidine-6-carboxylic acid, 4-amino-, methyl ester; CAS 155087-15-3
EINECS	Contact for details

Quality Control

Our Methyl 4-Aminothieno[2,3-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP guidelines for early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.