Description

2-Bromo-5-Phenylpyrimidine is a versatile halogenated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its ability to act as a key intermediate in the construction of complex molecules, particularly through cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the creation of organic electronic materials, such as ligands for OLEDs and other optoelectronic devices.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form new carbon-carbon and carbon-nitrogen bonds.
• Ligand Synthesis: Employed in the development of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Used as a probe or tag in medicinal chemistry and biochemical research for studying biological pathways.

Basic Information

Product Name	2-Bromo-5-Phenylpyrimidine
CAS No.	155079-14-4
Molecular Formula	C10H7BrN2
Molecular Weight	235.08 g/mol
Synonyms	5-Phenyl-2-bromopyrimidine; 2-Bromo-5-phenyl-1,3-diazine; Pyrimidine, 2-bromo-5-phenyl-; 155079-14-4; 2-Brom-5-phenylpyrimidin; 2-Bromo-5-fenylpyrimidine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Phenylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.