Description

Calcitonin (8-32) (Salmon I) is a specific, biologically active fragment of the salmon calcitonin peptide hormone. This compound is of significant value for research and development in the fields of endocrinology and bone metabolism. It serves as a critical reference standard and tool compound for scientists and pharmaceutical developers studying calcium regulation, osteoporosis, and related metabolic disorders.

Application

• Biomedical Research: Used as a reference standard in studies investigating the structure-activity relationship (SAR) of calcitonin peptides and their receptor interactions.
• Pharmacological Studies: Employed in in vitro and in vivo assays to understand the biological effects of calcitonin fragments on calcium homeostasis and bone resorption.
• Analytical Chemistry: Serves as a high-purity calibrant and system suitability standard in chromatographic (HPLC, LC-MS) and spectroscopic analyses for peptide quantification and identification.
• Drug Discovery & Development: Acts as a key intermediate or precursor in the research and synthesis of novel therapeutic peptides targeting metabolic bone diseases.
• Quality Control: Utilized by manufacturers as an impurity marker or reference compound in the quality assurance of full-length salmon calcitonin API (Active Pharmaceutical Ingredient) production.

Basic Information

Product Name	Calcitonin (8-32) (Salmon I)
CAS No.	155069-90-2
Molecular Formula	C₁₄₅H₂₄₀N₄₄O₄₇S₂
Molecular Weight	~3300.8 g/mol
Synonyms	Salmon Calcitonin (8-32); sCT (8-32); H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH₂ (Disulfide bridge: Cys1-Cys7); Calcitonin salmon fragment 8-32
EINECS	Contact for details

Quality Control

Our Calcitonin (8-32) (Salmon I) is produced under stringent conditions to ensure the highest standards of purity and consistency, suitable for critical research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality protocols to guarantee batch-to-batch reproducibility.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Related Peptides (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.